A sequence-specific gene refers to a gene that is regulated or influenced by a specific DNA sequence within its promoter or regulatory regions. These specific sequences, known as cis-regulatory elements or binding sites, are recognized by sequence-specific DNA-binding proteins, such as transcription factors, which bind to them and modulate gene expression.

The binding of transcription factors to these sequence-specific elements can either activate or repress the transcription of the target gene, depending on the nature of the regulatory elements and the transcription factors involved. This regulation plays a crucial role in various cellular processes such as development, differentiation, and response to environmental stimuli.

Studying sequence-specific genes and their regulatory elements can provide insights into the mechanisms of gene regulation and contribute to our understanding of complex biological processes, as well as aid in the development of gene therapies and other medical applications.